Vol. 30 No. 2
Special Issue on Retinal Prosthesis
Guest Editor: Jun Ohta (Nara Institute of Science and Technology), Hiroyuki Tashiro (Kyushu University), and Yasuo Terasawa (Nidek Co., Ltd.)
The metabolism of an organism is regulated at the cellular level, yet is strongly influenced by its environment. The precise metabolomic study of living organisms is currently hampered by measure ... Read More
A smart electrode that has a built-in CMOS microchip was fabricated for use as a retinal stimulator used in retinal prostheses. The CMOS microchip was embedded into the core of a bullet-shaped st ... Read More
Electronic retinal implants have been developed and are marketed as a therapeutic option for blind people suffering from degenerative retinal diseases such as retinitis pigmentosa. The functional ... Read More
A CMOS implantable chip with 256 active pixel sensors (APSs), on-chip photovoltaic cells, and iridium-oxide (IrOx) electrodes is proposed and designed for subretinal prostheses. In the proposed c ... Read More
The geometry dependence and three-dimensionalized effect of the electrochemical properties of iridium oxide electrodes used in retinal prosthesis are discussed herein. Planar electrodes with vari ... Read More
To realize a three-dimensionally (3D) stacked retinal prosthesis chip having a large stimulus electrode area and a large photodiode area, the fundamental properties of Al-doped ZnO transparent st ... Read More
We have been developing a retinal prosthesis based on suprachoroidal transretinal stimulation (STS). From a practical viewpoint, it is essential to confirm the safety and effectiveness of continu ... Read More
We developed a visual prosthesis based on suprachoroidal transretinal stimulation (STS) using electrodes width femtosecond-laser-induced porosity (FLiP electrodes). A current of 1.5 mA (1.25 time ... Read More
In this paper, we present a novel stimulation controller and monitoring system for evaluating the safety and efficacy of implantable neuroprosthetic devices in a preclinical setting. It features ... Read More
The development of a visual prosthesis requires long-term safety evaluation. Functional evaluation using evoked potential, such as visual evoked potential (VEP) and electrical evoked potential, i ... Read More
OFF-type bipolar cells (OFF-BCs) are interneurons connecting cone and retinal ganglion cells in the retina. In the mammalian retina, the cone signals are received by alpha-amino- 3-hydroxy-5-meth ... Read More
Retinal prostheses for blindness electrically stimulate retinas with photoreceptor cell degeneration to evoke a pseudolight sensation (phosphenes). Biphasic symmetric pulses with charge balancing ... Read More
S&M148230th Commemorative Article |
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S&M1482 Nuclear Magnetic Resonance Microscopy for In Vivo Metabolomics, Digitally Twinned by Computational Systems Biology, Needs a Sensitivity Boost Jan Gerrit Korvink, Vlad Badilita, Lorenzo Bordonali, Mazin Jouda, Dario Mager, and Neil MacKinnon pp. 157-166 https://doi.org/10.18494/SAM.2018.1711 Published on January 26, 2018 PDF (open access) |
S&M1483Research Paper of Special Issue |
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S&M1483 Functional Validation of Intelligent Retinal Stimulator Using Microchip-embedded Smart Electrode Toshihiko Noda, Makito Haruta, Kiyotaka Sasagawa, Takashi Tokuda, and Jun Ohta pp. 167-177 https://doi.org/10.18494/SAM.2018.1649 Published on January 26, 2018 PDF (open access) |
S&M1484Research Paper of Special Issue |
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S&M1484 Functionality and Performance of the Subretinal Implant Chip Alpha AMS Renate Daschner, Albrecht Rothermel, Ralf Rudorf, Sandra Rudorf, and Alfred Stett pp. 179-192 https://doi.org/10.18494/SAM.2018.1726 Published on January 26, 2018 PDF (open access) |
S&M1485Research Paper of Special Issue |
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S&M1485 A CMOS 256-pixel Photovoltaics-powered Implantable Chip with Active Pixel Sensors and Iridium-oxide Electrodes for Subretinal Prostheses Chung-Yu Wu, Po-Han Kuo, Po-Kang Lin, Po-Chun Chen, Wei-Jie Sung, Jun Ohta, Takashi Tokuda, and Toshihiko Noda pp. 193-211 https://doi.org/10.18494/SAM.2018.1664 Published on January 26, 2018 PDF (open access) |
S&M1486Research Paper of Special Issue |
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S&M1486 Electrochemical Evaluation of Geometrical Effect and Three-dimensionalized Effect of Iridium Oxide Electrodes Used for Retinal Stimulation Toshihiko Noda, Yoshiko Noda, Po-Chun Chen, Makito Haruta, Kiyotaka Sasagawa, Takashi Tokuda, Chung-Yu Wu, and Jun Ohta pp. 213-224 https://doi.org/10.18494/SAM.2018.1717 Published on January 26, 2018 PDF (open access) |
S&M1487Research Paper of Special Issue |
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S&M1487 Study of Al-doped ZnO Transparent Stimulus Electrode for Fully Implantable Retinal Prosthesis with Three-dimensionally Stacked Retinal Prosthesis Chip Hisashi Kino, Takafumi Fukushima, and Tetsu Tanaka pp. 225-234 https://doi.org/10.18494/SAM.2018.1741 Published on January 26, 2018 PDF (open access) |
S&M1488Research Paper of Special Issue |
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S&M1488 Safety and Efficacy of Semichronic Suprachoroidal Transretinal Stimulation with Femtosecond Laser-induced Porosity and Smooth-surface Electrodes Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, and Jun Ohta pp. 235-249 https://doi.org/10.18494/SAM.2018.1652 Published on January 26, 2018 PDF (open access) |
S&M1489Research Paper of Special Issue |
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S&M1489 In Vitro and In Vivo Long-term Electrochemical Properties of Electrodes with Femtosecond-laser-induced Porosity for Visual Prostheses Based on Suprachoroidal Transretinal Stimulation Hiroyuki Tashiro, Mariko Kuwabara, Yukari Nakano, Yasuo Terasawa, Koji Osawa, Yurina Yoshimura, Haruna Doi, and Jun Ohta pp. 251-268 https://doi.org/10.18494/SAM.2018.1723 Published on January 26, 2018 PDF (open access) |
S&M1490Research Paper of Special Issue |
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S&M1490 A Flexible Wireless System for Preclinical Evaluation of Retinal Prosthesis Patrick C. Thien, Rodney E. Millard, Stephanie B. Epp, David A. X. Nayagam pp. 269-286 https://doi.org/10.18494/SAM.2018.1651 Published on January 26, 2018 PDF (open access) |
S&M1491Research Paper of Special Issue |
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S&M1491 Comparative Study of Sevoflurane and Isoflurane Anesthesia for the Long-term Safety Evaluation of Visual Prosthesis with Rabbits Mariko Kuwabara, Hiroyuki Tashiro, Yukari Nakano, Yasuo Terasawa, Hajime Sawai, and Jun Ohta pp. 287-297 https://doi.org/10.18494/SAM.2018.1715 Published on January 26, 2018 PDF (open access) |
S&M1492Research Paper of Special Issue |
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S&M1492 Simulation Analysis of Temporal Coding by Ionotropic Glutamate Receptors of Retinal OFF-type Bipolar Cells Akito Ishihara pp. 299-313 https://doi.org/10.18494/SAM.2018.1720 Published on January 26, 2018 PDF (open access) |
S&M1493Research Paper of Special Issue |
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S&M1493 Effects of an Asymmetric Electrical Pulse on Retinal Excitement for Retinal Prostheses Yukari Nakano, Yasuo Terasawa, Hiroyuki Kanda, Jun Ohta, Hajime Sawai, and Takashi Fujikado pp. 315-326 https://doi.org/10.18494/SAM.2018.1701 Published on January 26, 2018 PDF (open access) |
Cover of this Issue |
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