pp. 209-218
S&M483 Research Paper in Biosensors and Related Areas Published: 2002 A Multifunctional Sensor-Chip based on Micromachined Chamber Array [PDF] Jianzhong Zhu, Ziqiang Zhu, Zongsheng Lai, Rong Wang, Xiaqin Wu Guoxiong Zhang and Zongrang Zhang Keywords: biosensor, potassium ion-selective-electrode, micromachining technology, chitosan membrane
This paper reports the fabrication and characterization of a sensor-chip based on a 2x2 microchamber array produced on silicon by anisotropic etching. The chip consists of a glucose sensor, a glutamate sensor, a galactose sensor and a potassium ion-selective-electrode. The structure of the microchamber-array has improved membrane adhesion and mechanical stability and can offer the place-selective immobilization of the enzymes. A chitosan membrane is used not only to immobilize the enzyme on the working electrode but also to prevent the penetration of interferents such as uric and ascorbic acids. The fabricated chips have shown attractive performances such as high sensitivity and good stability.
Cite this article Jianzhong Zhu, Ziqiang Zhu, Zongsheng Lai, Rong Wang, Xiaqin Wu Guoxiong Zhang and Zongrang Zhang, A Multifunctional Sensor-Chip based on Micromachined Chamber Array, Sens. Mater., Vol. 14, No. 4, 2002, p. 209-218. |