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Print: ISSN 0914-4935
Online: ISSN 2435-0869
Sensors and Materials
is an international peer-reviewed open access journal to provide a forum for researchers working in multidisciplinary fields of sensing technology.
Online: ISSN 2435-0869
Sensors and Materials
is an international peer-reviewed open access journal to provide a forum for researchers working in multidisciplinary fields of sensing technology.
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Sensors and Materials
is covered by Science Citation Index Expanded (Clarivate Analytics), Scopus (Elsevier), and other databases.
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Sensors and Materials
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is covered by Science Citation Index Expanded (Clarivate Analytics), Scopus (Elsevier), and other databases.
Instructions to authors
English 日本語
Instructions for manuscript preparation
English 日本語
Template
English
Publisher
MYU K.K.
Sensors and Materials
1-23-3-303 Sendagi,
Bunkyo-ku, Tokyo 113-0022, Japan
Tel: 81-3-3827-8549
Fax: 81-3-3827-8547
MYU Research, a scientific publisher, seeks a native English-speaking proofreader with a scientific background. B.Sc. or higher degree is desirable. In-office position; work hours negotiable. Call 03-3827-8549 for further information.
MYU Research
(proofreading and recording)
MYU K.K.
(translation service)
The Art of Writing Scientific Papers
(How to write scientific papers)
(Japanese Only)
Sensors and Materials, Volume 27, Number 7 (2015)
Copyright(C) MYU K.K.
Copyright(C) MYU K.K.
|
pp. 575-583
S&M1092 Research Paper https://doi.org/10.18494/SAM.2015.1185 Published: August 11, 2015 Fabrication and Characterization of an Extended-Gate AlGaN/GaN-Based Heterostructure Field-Effect Transistor-Type Biosensor for Detecting Immobilized Streptavidin-Biotin Protein Complexes [PDF] Hee Ho Lee, Myunghan Bae, Sung-Hyun Jo, Jang-Kyoo Shin, Dong Hyeok Son, Chul-Ho Won and Jung-Hee Lee (Received March 23, 2015; Accepted June 15, 2015) Keywords: AlGaN/GaN, HFET, biosensor, extended-gate structure, streptavidin-biotin complexes
In this study, we fabricated an AlGaN/GaN-based heterostructure field-effect transistor (HFET)-type biosensor with an extended-gate structure for detecting streptavidin-biotin complexes. The gate voltage of the fabricated device was applied using a commercial Ag/AgCl reference electrode. The binding of a self-assembled monolayer (SAM), streptavidin and biotin was detected by measuring the electrical characteristics of the fabricated biosensor. X-ray photoelectron spectroscopy (XPS) was used to verify the immobilization of the SAM on the Au-coated GaN surface. The proposed biosensor shows that biotin can be detected for a wide range of concentrations from 0.1 to 1000 ng/ml. The long-term stability of both the extended-gate AlGaN/GaN-based HFET-type and conventional AlGaN/GaN-based HFET-type biosensors was measured in phosphate-buffered saline (PBS) solution. A high sensitivity and excellent stability of the proposed biosensor has been experimentally verified.
Corresponding author: Jang-Kyoo Shin Cite this article Hee Ho Lee, Myunghan Bae, Sung-Hyun Jo, Jang-Kyoo Shin, Dong Hyeok Son, Chul-Ho Won and Jung-Hee Lee, Fabrication and Characterization of an Extended-Gate AlGaN/GaN-Based Heterostructure Field-Effect Transistor-Type Biosensor for Detecting Immobilized Streptavidin-Biotin Protein Complexes, Sens. Mater., Vol. 27, No. 7, 2015, p. 575-583. |
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