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Print: ISSN 0914-4935
Online: ISSN 2435-0869
Sensors and Materials
is an international peer-reviewed open access journal to provide a forum for researchers working in multidisciplinary fields of sensing technology.
Online: ISSN 2435-0869
Sensors and Materials
is an international peer-reviewed open access journal to provide a forum for researchers working in multidisciplinary fields of sensing technology.
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Sensors and Materials
is covered by Science Citation Index Expanded (Clarivate Analytics), Scopus (Elsevier), and other databases.
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Sensors and Materials
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is covered by Science Citation Index Expanded (Clarivate Analytics), Scopus (Elsevier), and other databases.
Instructions to authors
English 日本語
Instructions for manuscript preparation
English 日本語
Template
English
Publisher
MYU K.K.
Sensors and Materials
1-23-3-303 Sendagi,
Bunkyo-ku, Tokyo 113-0022, Japan
Tel: 81-3-3827-8549
Fax: 81-3-3827-8547
MYU Research, a scientific publisher, seeks a native English-speaking proofreader with a scientific background. B.Sc. or higher degree is desirable. In-office position; work hours negotiable. Call 03-3827-8549 for further information.
MYU Research
(proofreading and recording)
MYU K.K.
(translation service)
The Art of Writing Scientific Papers
(How to write scientific papers)
(Japanese Only)
Sensors and Materials, Volume 30, Number 10(2) (2018)
Copyright(C) MYU K.K.
Copyright(C) MYU K.K.
|
pp. 2321-2331
S&M1678 Research Paper of Special Issue https://doi.org/10.18494/SAM.2018.1938 Published: October 25, 2018 Aptamer-functionalized AlGaN/GaN High-electron-mobility Transistor for Rapid Diagnosis of Fibrinogen in Human Plasma [PDF] Tse-Yu Tai, Anirban Sinha, Indu Sarangadharan, Anil Kumar Pulikkathodi, Shin-Li Wang, Shu-Chu Shiesh, Gwo-Bin Lee, and Yu-Lin Wang (Received March 5, 2018; Accepted June 28, 2018) Keywords: cardiovascular disease, fibrinogen, aptamer, AlGaN/GaN HEMT biosensor, in-vitro diagnostics
In this research, we have developed a rapid diagnostic assay using a high-electron-mobility transistor (HEMT)-based biosensor to screen for fibrinogen in clinical plasma samples. High sensitivity over a wide detection range (0–5 g/L), good selectivity, low-cost fabrication, portability, and simplicity of use are key features of our biosensor. Early diagnosis of heart disease in low-, medium-, and high-risk patients is possible with an assay turn-around time of 5 min and a plasma sample volume of 5–10 µL. High sensitivity and low detection limits (0.5 g/L) are made possible in environments with high salt concentrations because the HEMT sensor design overcomes the charge screening effect associated with a very small Debye length. This biosensor technology demonstrates the potential for development as a point-of-care or home-care diagnostic device for quick and easy assessment of cardiovascular disease (CVD) risk.
Corresponding author: Gwo-Bin Lee, Yu-Lin Wang Cite this article Tse-Yu Tai, Anirban Sinha, Indu Sarangadharan, Anil Kumar Pulikkathodi, Shin-Li Wang, Shu-Chu Shiesh, Gwo-Bin Lee, and Yu-Lin Wang, Aptamer-functionalized AlGaN/GaN High-electron-mobility Transistor for Rapid Diagnosis of Fibrinogen in Human Plasma, Sens. Mater., Vol. 30, No. 10, 2018, p. 2321-2331. |
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