pp. 861-871
S&M3568 Research Paper of Special Issue https://doi.org/10.18494/SAM4851 Published: March 8, 2024 Development of a Smartphone-linked Optical Biosensing System for Point-of-care Testing Applications [PDF] Miku Sarubo, Yuka Numazaki, and Hiroyuki Kudo (Received January 10, 2024; Accepted March 4, 2024) Keywords: biosensor, colorimetric, point-of-care, smartphone
We report a miniaturized batteryless colorimetric biosensing system for measuring saliva components. Our system utilizes a CMOS image sensor and an LED light source embedded in smartphones as a part of the optical system. We measured the concentration of chemical substances by observing color changes of the coloring reagent DA-64, which is specific for hydrogen peroxide. The concentration calculated from the RGB scores of colorimetric images showed strong correlations (r > 0.95) with the concentrations of the samples. This result shows the possibility of biochemical measurements using miniaturized biosensing systems to determine physiological conditions
Corresponding author: Hiroyuki KudoThis work is licensed under a Creative Commons Attribution 4.0 International License. Cite this article Miku Sarubo, Yuka Numazaki, and Hiroyuki Kudo, Development of a Smartphone-linked Optical Biosensing System for Point-of-care Testing Applications, Sens. Mater., Vol. 36, No. 3, 2024, p. 861-871. |