pp. 235-249
S&M1488 Research Paper of Special Issue https://doi.org/10.18494/SAM.2018.1652 Published: January 26, 2018 Safety and Efficacy of Semichronic Suprachoroidal Transretinal Stimulation with Femtosecond Laser-induced Porosity and Smooth-surface Electrodes [PDF] Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, and Jun Ohta (Received June 30, 2017; Accepted August 29, 2017) Keywords: retinal prosthesis, suprachoroidal transretinal stimulation, electrodes
We have been developing a retinal prosthesis based on suprachoroidal transretinal stimulation (STS). From a practical viewpoint, it is essential to confirm the safety and effectiveness of continuous electrical stimulation to the retina. In this study, the electrical stimulation of a rabbit retina for 8 h a day was conducted for one month, and its safety and efficacy were evaluated by histological, electrophysiological, and electrochemical methods. Results suggested that one month of semichronic electrical stimulation by STS was safe and effective.
Corresponding author: Yasuo TerasawaCite this article Yasuo Terasawa, Hiroyuki Tashiro, Yukari Nakano, and Jun Ohta, Safety and Efficacy of Semichronic Suprachoroidal Transretinal Stimulation with Femtosecond Laser-induced Porosity and Smooth-surface Electrodes, Sens. Mater., Vol. 30, No. 2, 2018, p. 235-249. |