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Print: ISSN 0914-4935
Online: ISSN 2435-0869
Sensors and Materials
is an international peer-reviewed open access journal to provide a forum for researchers working in multidisciplinary fields of sensing technology.
Online: ISSN 2435-0869
Sensors and Materials
is an international peer-reviewed open access journal to provide a forum for researchers working in multidisciplinary fields of sensing technology.
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Sensors and Materials
is covered by Science Citation Index Expanded (Clarivate Analytics), Scopus (Elsevier), and other databases.
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MYU K.K.
Sensors and Materials
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is covered by Science Citation Index Expanded (Clarivate Analytics), Scopus (Elsevier), and other databases.
Instructions to authors
English 日本語
Instructions for manuscript preparation
English 日本語
Template
English
Publisher
MYU K.K.
Sensors and Materials
1-23-3-303 Sendagi,
Bunkyo-ku, Tokyo 113-0022, Japan
Tel: 81-3-3827-8549
Fax: 81-3-3827-8547
MYU Research, a scientific publisher, seeks a native English-speaking proofreader with a scientific background. B.Sc. or higher degree is desirable. In-office position; work hours negotiable. Call 03-3827-8549 for further information.
MYU Research
(proofreading and recording)
MYU K.K.
(translation service)
The Art of Writing Scientific Papers
(How to write scientific papers)
(Japanese Only)
Sensors and Materials, Volume 31, Number 2(1) (2019)
Copyright(C) MYU K.K.
Copyright(C) MYU K.K.
|
pp. 311-318
S&M1772 Research Paper of Special Issue https://doi.org/10.18494/SAM.2019.2094 Published: February 8, 2019 Development of Polycaprolactone Microspheres with Controllable and Uniform Particle Size by Uniform Design Experiment in Emulsion Progress [PDF] Cheng-Tang Pan, Yeong-Maw Hwang, Yu-Min Lin, Song-Wei Zeng, Shao-Yu Wang, Shiao-Wei Kuo, Shin-Pon Ju, Shih-Shin Liang, Zong-Hsin Liu, and Chung-Kun Yen (Received May 30, 2018; Accepted October 11, 2018) Keywords: polycaprolactone, emulsification, uniform design experiment, spherical carrier
In this study, we propose a method of manufacturing spherical carriers with controllable and uniform particle size. Emulsification and a uniform design experiment were carried out to obtain the optimal fabrication process. The results show that a stable emulsification of oil in water (O/W) was achieved with an ~18.18 wt% polycaprolactone (PCL) oil solution and an ~13.02 wt% polyvinyl alcohol (PVA) aqueous solution. Finally, the uniformity of the PCL microcarriers was ~87.9% with a particle size range of 10−20 μm. In the future, medical carriers will be loaded with different officially approved medicines. The carriers could improve the bioavailability of pharmaceutical products, extend the duration of their effectivity due to drug and minimize their side effects.
Corresponding author: Chung-Kun Yen  This work is licensed under a Creative Commons Attribution 4.0 International License. Cite this article Cheng-Tang Pan, Yeong-Maw Hwang, Yu-Min Lin, Song-Wei Zeng, Shao-Yu Wang, Shiao-Wei Kuo, Shin-Pon Ju, Shih-Shin Liang, Zong-Hsin Liu, and Chung-Kun Yen, Development of Polycaprolactone Microspheres with Controllable and Uniform Particle Size by Uniform Design Experiment in Emulsion Progress, Sens. Mater., Vol. 31, No. 2, 2019, p. 311-318. |
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