pp. 3133-3140
S&M3028 Research Paper of Special Issue https://doi.org/10.18494/SAM3894 Published in advance: May 16, 2022 Published: August 15, 2022 Improved Stability of Continuous Operation of Lactate Oxidase-hydrogel Electrodes Using Os(bipyridine)2Cl-pendant Poly(vinyl Imidazole) [PDF] Ryunosuke Terazawa, Tsutomu Mikawa, and Seiya Tsujimura (Received March 16, 2022; Accepted April 25, 2022) Keywords: lactate oxidase, lactate sensor, redox hydrogel, stability, cross-linker
Hydrogel-modified redox electrodes are fabricated using lactate oxidase and a poly(vinyl imidazole) polymer containing an Os(bipyridine)2Cl complex to facilitate the improved continuous measurement of lactate concentration. The stability of a MgO-templated carbon modified with a hydrogel was improved by quaternizing 10 mol% of the imidazole content of poly(vinyl imidazole) with bromoethylamine. Stability was further improved by cross-linking the polymer using ethylene glycol diglycidyl ether and sorbitol polyglycidyl ether, which increased the density of the hydrogel structure.
Corresponding author: Seiya TsujimuraThis work is licensed under a Creative Commons Attribution 4.0 International License. Cite this article Ryunosuke Terazawa, Tsutomu Mikawa, and Seiya Tsujimura, Improved Stability of Continuous Operation of Lactate Oxidase-hydrogel Electrodes Using Os(bipyridine)2Cl-pendant Poly(vinyl Imidazole), Sens. Mater., Vol. 34, No. 8, 2022, p. 3133-3140. |