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Notice of retraction
Vol. 34, No. 8(3), S&M3042

Notice of retraction
Vol. 32, No. 8(2), S&M2292

Print: ISSN 0914-4935
Online: ISSN 2435-0869
Sensors and Materials
is an international peer-reviewed open access journal to provide a forum for researchers working in multidisciplinary fields of sensing technology.
Sensors and Materials
is covered by Science Citation Index Expanded (Clarivate Analytics), Scopus (Elsevier), and other databases.

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Sensors and Materials, Volume 33, Number 1(2) (2021)
Copyright(C) MYU K.K.
pp. 171-180
S&M2443 Research Paper of Special Issue
https://doi.org/10.18494/SAM.2021.3067
Published: January 22, 2021

Alamethicin Channels as a Signal Transduction Element in an Immobilized Single Giant Unilamellar Vesicle [PDF]

Hiroyuki Fukuda, Masaki Nitta, Misato Sakamoto, Atsushi Shoji, and Masao Sugawara

(Received August 31, 2020; Accepted December 2, 2020)

Keywords: single giant unilamellar vesicle, alamethicin channel, bovine serum albumin, avidin slip

A single giant unilamellar vesicle (GUV) functionalized with an anti-bovine serum albumin (BSA) antibody was immobilized on an avidin slip, and alamethicin channels were embedded as a signal transduction element for creating a channel-based molecular sensing system. The GUV sensor based on the membrane-bound anti-BSA antibody receptor exhibited alamethicin activities that reflected the binding of BSA (an analyte) at the membrane/solution interface. The normalized integrated current at −60 mV was able to be used as a measure of the amount of BSA in a solution. The quantification of BSA at pg/mL level was demonstrated.

Corresponding author: Atsushi Shoji


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Cite this article
Hiroyuki Fukuda, Masaki Nitta, Misato Sakamoto, Atsushi Shoji, and Masao Sugawara, Alamethicin Channels as a Signal Transduction Element in an Immobilized Single Giant Unilamellar Vesicle, Sens. Mater., Vol. 33, No. 1, 2021, p. 171-180.



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