pp. 3383-3396
S&M3047 Research Paper https://doi.org/10.18494/SAM3983 Published: September 6, 2022 Device to Collect Skin Cells Using Ultrasound Irradiation and Aspiration [PDF] Yang Ye, Tatsuya Uechi, Noriko Tsuruoka, Makoto Akashi, and Yoichi Haga (Received June 29, 2022; Accepted July 27, 2022) Keywords: ultrasound, cavitation, cell collection, fine needle, minimally invasive
Dynamic cell activity can be examined by collecting and analyzing cells every few hours during the day. However, current techniques to extract and analyze skin cells are deemed ineffective and/or invasive. Thus, in this study, we designed and fabricated a device that collects skin cells using ultrasound irradiation. An ultrasonic horn amplifies a Langevin transducer, which then generates ultrasound and transmits it to a fine needle. Ultrasound is irradiated from the needle to the body surface, and ultrasonic oscillation and cavitation cut or weaken intercellular binding. We successfully aspirated 30 cells from pig skin using our minimally invasive device.
Corresponding author: Yang YeThis work is licensed under a Creative Commons Attribution 4.0 International License. Cite this article Yang Ye, Tatsuya Uechi, Noriko Tsuruoka, Makoto Akashi, and Yoichi Haga , Device to Collect Skin Cells Using Ultrasound Irradiation and Aspiration, Sens. Mater., Vol. 34, No. 9, 2022, p. 3383-3396. |