pp. 295-311
S&M530 Research Paper of Special Issue Published: 2003 Integrated Fabrication of Polymeric Devices for Biological Applications [PDF] Mark J. Kastantin, Sheng Li, Anand P. Gadre, Li-Qun Wu, William E. Bentley, Gregory F. Payne, Gary W. Rubloff and Reza Ghodssi (Received May 8, 2003; Accepted July 22, 2003) Keywords: integrative polymeric fabrication, SU-8, polypyrrole (PPy), polydimethylsiloxane (PDMS), chitosan, green fluorescent protein (GFP), bonding
A novel fabrication technique for all-polymeric, microfluidic bio-MEMS devices is presented. This device uses selective electrodeposition of a bio-polymer, chitosan, to successfully create an environment for complex biological experiments within an SU-8 microchannel. The surface energy between SU-8 and PDMS is measured to be 0.047 + 0.018 J/m2, allowing for reversible encapsulation of the microfluidic channel. The con- ducting material, polypyrrole, has a conductivity of 47 + 5 S/cm and is explored as a replacement for metal electrodes in future work. It is the successful integration of these four polymers, however, that enables such versatile devices to be fabricated.
Corresponding author: Reza GhodssiCite this article Mark J. Kastantin, Sheng Li, Anand P. Gadre, Li-Qun Wu, William E. Bentley, Gregory F. Payne, Gary W. Rubloff and Reza Ghodssi, Integrated Fabrication of Polymeric Devices for Biological Applications, Sens. Mater., Vol. 15, No. 6, 2003, p. 295-311. |